Anti-NAE1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K010328P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-NAE1 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8883 | 【Swiss Prot】：Q13564 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-4000. | |
| 【Immunogen】：Recombinant protein of human NAE1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
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