Anti-LOX Polyclonal Antibody - Cy3.5
Cat: K010395P - Cy3.5
Summary:
| 【Product name】：Anti-LOX Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4015 | 【Swiss Prot】：P28300 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human LOX | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
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