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Anti-BMP6 Polyclonal Antibody - RBITC
Cat: K010409P - RBITC
Summary:
【Product name】:Anti-BMP6 Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:654 【Swiss Prot】:P22004
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human BMP6
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
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