Anti-NPHS2 Polyclonal Antibody - SAlexa Fluor 405
Cat: K010442P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-NPHS2 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7827 | 【Swiss Prot】：Q9NP85 |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:50-200. ELISA 1:2000-5000. | |
| 【Immunogen】：A synthetic peptide of human NPHS2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
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