Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody - SAlexa Fluor 647
Cat: K010452P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5594/5595 | 【Swiss Prot】：P28482/P27361 |
| 【Observed】：43kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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