Anti-SCN4A Polyclonal Antibody
Cat: K113644P
Summary:
| 【Product name】：Anti-SCN4A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6329 | 【Swiss Prot】：P35499 |
| 【Observed】：230-260kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：A synthetic peptide of human SCN4A | |
| 【Public Immunogen Range】：300-350/1836aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Pore-forming subunit of a voltage-gated sodium channel complex through which Na+ ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states (PubMed:12766226, PubMed:29992740, PubMed:30190309, PubMed:15318338, PubMed:16890191, PubMed:18690054, PubMed:17898326, PubMed:19347921, PubMed:25707578, PubMed:26700687).Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K+ levels (PubMed:12766226, PubMed:15318338, PubMed:16890191, PubMed:19347921, PubMed:25707578, PubMed:26700687, PubMed:26659129).
Verified picture:
Western blot analysis with SCN4A antibody diluted at 1:1000;Lane: THP-1,K-562,COLO205,MCF7.