Anti-AIMP2 Polyclonal Antibody - SAlexa Fluor 488
Cat: K113668P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-AIMP2 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7965 | 【Swiss Prot】：Q13155 |
| 【Observed】：30kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human AIMP2 | |
| 【Public Immunogen Range】：150-200/320aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:19131329).Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
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