Background:
Acyltransferase that regulates cellular triglyceride (TG) content and glycerolipid composition via the monoglyceride pathway. Primarily acyl-CoA:monoacylglycerol acyltransferase (MGAT), but can also exhibit acyl-CoA:diacylglycerol acyltransferase (DGAT) activity. By regulating the synthesis of diglyceride precursors, it may affect the levels of glycerophospholipids such as phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine. Plays a role in lipogenesis by inducing the expression of some key regulators such as diglyceride acyltransferases (DGATs) and enzymes of de novo fatty acid synthesis.