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Anti-PABPC1 Polyclonal Antibody
Cat: K113700P
Summary:
【Product name】:Anti-PABPC1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:26986 【Swiss Prot】:P11940
【Observed】:75kDa
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human PABPC1
【Public Immunogen Range】:1-400aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
Verified picture:
Western blot analysis with PABPC1 antibody diluted at 1:2000;Lane: Mouse pancreas,Mouse testis,Rat testis.
Immunohistochemistry of paraffin-embedded human colorectal cancer with PABPC1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human endometrial cancer with PABPC1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human thyroid cancer with PABPC1 antibody diluted at 1:100.