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Anti-CACNA2D1 Polyclonal Antibody
Cat: K113731P
Summary:
【Product name】:Anti-CACNA2D1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:781 【Swiss Prot】:P54289
【Observed】:125kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human CACNA2D1
【Public Immunogen Range】:500-850aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion.
Verified picture:
Western blot analysis with CACNA2D1 antibody diluted at 1:2000;Lane: 293T,L-02,Mouse brain,Rat brain,SH-SY5Y.
Immunohistochemistry of paraffin-embedded human colorectal cancer with CACNA2D1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human endometrial cancer with CACNA2D1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human thyroid cancer with CACNA2D1 antibody diluted at 1:100.