Anti-SYTL2 Polyclonal Antibody - SAlexa Fluor 555
Cat: K113769P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-SYTL2 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：54843 | 【Swiss Prot】：Q9HCH5 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human SYTL2 | |
| 【Public Immunogen Range】：1-377aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca2+ while binding to PIP2 is Ca2+ insensitive.
Verified picture: