Anti-PLK1 Polyclonal Antibody
Cat: K113799P
Summary:
| 【Product name】：Anti-PLK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5347 | 【Swiss Prot】：P53350 |
| 【Observed】：63kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human PLK1 | |
| 【Public Immunogen Range】：485-535/603aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Verified picture:
Western blot analysis with PLK1 antibody diluted at 1:3000;Lane: Jurkat,Raji,Vero,K-562.
Immunohistochemistry of paraffin-embedded human liver cancer with PLK1 antibody diluted at 1:50.