Anti-PLK1 Polyclonal Antibody - SAlexa Fluor 680
Cat: K113799P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-PLK1 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5347 | 【Swiss Prot】：P53350 |
| 【Observed】：63kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human PLK1 | |
| 【Public Immunogen Range】：485-535/603aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
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