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Anti-RFIP2 Polyclonal Antibody - SAlexa Fluor 633
Cat: K113801P - SAlexa Fluor 633
Summary:
【Product name】:Anti-RFIP2 Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:22841 【Swiss Prot】:Q7L804
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of human RFIP2
【Public Immunogen Range】:200-250/512aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.
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