Anti-GDIB Polyclonal Antibody
Cat: K113807P
Summary:
| 【Product name】：Anti-GDIB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2665 | 【Swiss Prot】：P50395 |
| 【Observed】：52kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human GDIB | |
| 【Public Immunogen Range】：210-260/445aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Verified picture:
Western blot analysis with GDIB antibody diluted at 1:2000;Lane: Rat brain,Rat liver.
Immunohistochemistry of paraffin-embedded human breast cancer with GDIB antibody diluted at 1:200.