Anti-ACTC Polyclonal Antibody
Cat: K113832P
Summary:
| 【Product name】：Anti-ACTC Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：58/59/60/70/71/72/345651 | 【Swiss Prot】：P68133/P62736/P60709/P68032/P63261/P63267/Q562R1 |
| 【Observed】：48kDa | |
| 【Tested applications】：WB;IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human ACTC | |
| 【Public Immunogen Range】：300-350/377aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
Verified picture:
Western blot analysis with ACTC antibody diluted at 1:2000;Lane: NIH3T3,C2C12,Mouse heart,Mouse skeletal muscle,Mouse skin,Rat heart,Rat lung.
Immunohistochemistry of paraffin-embedded human breast cancer with ACTC antibody diluted at 1:100.