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Anti-PRKAA1/PRKAA2 Polyclonal Antibody - SAlexa Fluor 568
Cat: K113864P - SAlexa Fluor 568
Summary:
【Product name】:Anti-PRKAA1/PRKAA2 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5562/5563 【Swiss Prot】:Q13131/P54646
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:A synthetic peptide of human PRKAA1/PRKAA2
【Public Immunogen Range】:450-500/559aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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