Anti-CHRNA10 Polyclonal Antibody - FITC
Cat: K113927P - FITC
Summary:
| 【Product name】：Anti-CHRNA10 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57053 | 【Swiss Prot】：Q9GZZ6 |
| 【Observed】：50kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CHRNA10 | |
| 【Public Immunogen Range】：55-105/450aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
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