Anti-FKBP8 Polyclonal Antibody - SAlexa Fluor 680
Cat: K113942P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-FKBP8 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23770 | 【Swiss Prot】：Q14318 |
| 【Observed】：46kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human FKBP8 | |
| 【Public Immunogen Range】：150-200/412aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Verified picture: