Anti-CALR Polyclonal Antibody - SAlexa Fluor 568
Cat: K010133P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-CALR Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：811 | 【Swiss Prot】：P27797 |
| 【Tested applications】：WB,FCM,ELISA,IHC,IF | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-500.FCM 0.40 ug per 10^6 cells in a 100 μl suspension. | |
| 【Immunogen】：Recombinant protein of human calreticulin | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
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