Anti-HMGB1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K010501P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-HMGB1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3146 | 【Swiss Prot】：P09429 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human HMGB1 | |
| 【Public Immunogen Range】：75-170/215aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models.
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