Anti-phospho-Alpha synuclein(Ser129) Polyclonal Antibody - SAlexa Fluor 488
Cat: K010498P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-phospho-Alpha synuclein(Ser129) Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6622 | 【Swiss Prot】：P37840 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human phospho-Alpha synuclein (Ser129) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
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