Anti-MSH2 Polyclonal Antibody
Cat: K114018P
Summary:
| 【Product name】：Anti-MSH2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4436 | 【Swiss Prot】：P43246 |
| 【Observed】：100kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human MSH2 | |
| 【Public Immunogen Range】：585-935aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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