Anti-PFKFB1 Polyclonal Antibody
Cat: K114131P
Summary:
| 【Product name】：Anti-PFKFB1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5207 | 【Swiss Prot】：P16118 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human PFKFB1 | |
| 【Public Immunogen Range】：340-390/471aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
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