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Anti-USP8 Polyclonal Antibody - SAlexa Fluor 750
Cat: K114251P - SAlexa Fluor 750
Summary:
【Product name】:Anti-USP8 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9101 【Swiss Prot】:P40818
【Observed】:128-135kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:2000-5000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human USP8
【Public Immunogen Range】:375-724aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
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