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Anti-AKAP13 Polyclonal Antibody - SAlexa Fluor 350
Cat: K114200P - SAlexa Fluor 350
Summary:
【Product name】:Anti-AKAP13 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:11214 【Swiss Prot】:Q12802
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human AKAP13
【Public Immunogen Range】:1850-1900/2813aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element-specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Isoform 6 stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
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