Anti-TNS2 Polyclonal Antibody - SAlexa Fluor 405
Cat: K114142P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-TNS2 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23371 | 【Swiss Prot】：Q63HR2 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human TNS2 | |
| 【Public Immunogen Range】：450-500/1409aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy (PubMed:23401856). Negatively regulates PI3K-AKT pathway activation (PubMed:15817639, PubMed:23401856)
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