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Anti-TNS2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K114142P - SAlexa Fluor 750
Summary:
【Product name】:Anti-TNS2 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23371 【Swiss Prot】:Q63HR2
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human TNS2
【Public Immunogen Range】:450-500/1409aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy (PubMed:23401856). Negatively regulates PI3K-AKT pathway activation (PubMed:15817639, PubMed:23401856)
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