Anti-KLHL20 Polyclonal Antibody
Cat: K113973P
Summary:
| 【Product name】：Anti-KLHL20 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：27252 | 【Swiss Prot】：Q9Y2M5 |
| 【Observed】：65kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human KLHL20 | |
| 【Public Immunogen Range】：1-176aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
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