Anti-UBAP1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K114071P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-UBAP1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51271 | 【Swiss Prot】：Q9NZ09 |
| 【Observed】：63kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human UBAP1 | |
| 【Public Immunogen Range】：30-380aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process (PubMed:21757351, PubMed:22405001, PubMed:31203368).Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (PubMed:21757351, PubMed:22405001).Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 (PubMed:24284069, PubMed:22405001, PubMed:31203368).
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