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Anti-RAD18 Polyclonal Antibody - Cy5.5
Cat: K114057P - Cy5.5
Summary:
【Product name】:Anti-RAD18 Polyclonal Antibody - Cy5.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:56852 【Swiss Prot】:Q9NS91
【Observed】:80kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human RAD18
【Public Immunogen Range】:145-495aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
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