Anti-GLYR1 Polyclonal Antibody - Biotin
Cat: K114330P - Biotin
Summary:
| 【Product name】：Anti-GLYR1 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：84656 | 【Swiss Prot】：Q49A26 |
| 【Observed】：65kDa | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GLYR1 | |
| 【Public Immunogen Range】：30-380aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation (PubMed:29759984).Facilitates Pol II transcription through nucleosomes (PubMed:29759984).Binds DNA (in vitro) (PubMed:29759984).Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016).Promotes KDM1B demethylase activity (PubMed:23260659).Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (PubMed:29759984).Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664).Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664).The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664).Putative oxidoreductase (PubMed:23260659).
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