下载
Anti-TMEM173 Polyclonal Antibody - SAlexa Fluor 633
Cat: K114101P - SAlexa Fluor 633
Summary:
【Product name】:Anti-TMEM173 Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:340061 【Swiss Prot】:Q86WV6
【Observed】:36kDa
【Tested applications】:IF,IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human TMEM173
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Verified picture: