Anti-Phospho-RIP3-S227 Polyclonal Antibody - Cy7
Cat: K011386P - Cy7
Summary:
| 【Product name】：Anti-Phospho-RIP3-S227 Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：11035 | 【Swiss Prot】：Q9Y572 |
| 【Tested applications】：IF,IHC | |
| 【Recommended dilution】：IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human Phospho-RIP3-S227 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
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