Anti-NKG7?Polyclonal Antibody - SAlexa Fluor 488
Cat: K011401P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-NKG7?Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4818 | 【Swiss Prot】：Q16617 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human NKG7 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity).Essential for cytotoxic degranulation of natural killer (NK) cells and CD8+ T-cells and for the activation of CD4+ T-cells following infection (By similarity).Plays a critical role in CD8+ T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity).
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