Anti-CLDN1 Polyclonal Antibody - SAlexa Fluor 680
Cat: K114626P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-CLDN1 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9076 | 【Swiss Prot】：O95832 |
| 【Observed】：19kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human CLDN1 | |
| 【Public Immunogen Range】：160-210/211aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
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