Anti-IL18BP Polyclonal Antibody - SAlexa Fluor 640
Cat: K114669P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-IL18BP Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10068 | 【Swiss Prot】：O95998 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human IL18BP | |
| 【Public Immunogen Range】：30-80/194aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohns disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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