Anti-Complement fragment 3c Polyclonal Antibody - SAlexa Fluor 350
Cat: K011358P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-Complement fragment 3c Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：718 | 【Swiss Prot】：P01024 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human Complement C3c alpha' chain fragment 1 | |
| 【Public Immunogen Range】：1051-1200/1663aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently，via its reactive thioester，to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3，C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle，increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
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