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Anti-UBE2M Polyclonal Antibody - RBITC
Cat: K114426P - RBITC
Summary:
【Product name】:Anti-UBE2M Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:9040 【Swiss Prot】:P61081
【Observed】:19kDa
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human UBE2M
【Public Immunogen Range】:1-184aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1,but not RBX2,suggests that the RBX1-UBE2M complex neddylates specific target proteins,such as CUL1,CUL2,CUL3 and CUL4. Involved in cell proliferation.
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