Anti-UBE2M Polyclonal Antibody - SAlexa Fluor 640
Cat: K114426P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-UBE2M Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：9040 | 【Swiss Prot】：P61081 |
| 【Observed】：19kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human UBE2M | |
| 【Public Immunogen Range】：1-184aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1，but not RBX2，suggests that the RBX1-UBE2M complex neddylates specific target proteins，such as CUL1，CUL2，CUL3 and CUL4. Involved in cell proliferation.
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