Anti-TRPM2 Polyclonal Antibody
Cat: K114461P
Summary:
| 【Product name】：Anti-TRPM2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7226 | 【Swiss Prot】：O94759 |
| 【Observed】：170kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TRPM2 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium，sodium，and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described，but their full-length nature is not known.
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