Anti-RGS17 Polyclonal Antibody - HRP
Cat: K114546P - HRP
Summary:
| 【Product name】：Anti-RGS17 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：26575 | 【Swiss Prot】：Q9UGC6 |
| 【Observed】：24kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RGS17 | |
| 【Public Immunogen Range】：1-211aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved，120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated，GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP)，increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers，forming inactive G-protein heterotrimers，thereby terminating the signal.
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