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Anti-CD38(APC) Monoclonal Antibody
Cat: K010601M
Summary:
【Product name】:Anti-CD38(APC) Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG1
【Gene ID】:952 【Swiss Prot】:P28907
【Tested applications】:FCM
【Recommended dilution】:FCM 5uL/Test.
【Storage】:Store at 4℃ in dark.Do not freeze.
Background:
The protein encoded by this gene is a non-lineage-restricted,type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose,an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail,a single membrane-spanning domain,and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer,with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq,Sep 2015]
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