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Anti-HLA-DR(PE-Cy5) Monoclonal Antibody - SAlexa Fluor 640
Cat: K010750M - SAlexa Fluor 640
Summary:
【Product name】:Anti-HLA-DR(PE-Cy5) Monoclonal Antibody - SAlexa Fluor 640 【Source】:Mouse
【Isotype】:IgG2b,κ
【Gene ID】:3122 【Swiss Prot】:P01903
【Tested applications】:FCM
【Recommended dilution】:FCM 5uL/Test.
【Storage】:Store at 4℃ in dark.Do not freeze.
Background:
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain,both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes,dendritic cells,macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide,exons 2 and 3 encode the two extracellular domains,and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1,DRB3,DRB4 and DRB5. [provided by RefSeq]
Verified picture: