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Anti-CD41(FITC) Monoclonal Antibody - SAlexa Fluor 488
Cat: K010800M - SAlexa Fluor 488
Summary:
【Product name】:Anti-CD41(FITC) Monoclonal Antibody - SAlexa Fluor 488 【Source】:Mouse
【Isotype】:IgG1
【Gene ID】:3674 【Swiss Prot】:P08514
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Storage】:Store at 4℃ in dark.Do not freeze.
Background:
Integrin alpha 2b (CD41) is a calcium-dependent,noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex,gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen,von Willebrand factor,fibronectin,vitronectin,and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
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