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Anti-CD53(FITC) Monoclonal Antibody - SAlexa Fluor 750
Cat: K010818M - SAlexa Fluor 750
Summary:
【Product name】:Anti-CD53(FITC) Monoclonal Antibody - SAlexa Fluor 750 【Source】:Mouse
【Isotype】:IgG2a
【Gene ID】:963 【Swiss Prot】:P19397
【Tested applications】:FCM
【Recommended dilution】:FCM 5uL/Test.
【Storage】:Store at 4℃ in dark.Do not freeze.
Background:
The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. The tetraspanin superfamily (CD9,CD37,CD53,CD63,CD81 and CD82) comprises a group of cell-surface proteins that are involved in cell activation and signal transduction as well as in cell adhesion,motility and metastasis. Tetraspanin transmembrane proteins have a metastasis suppressor effect by acting as cell motility brakes in tumor cells. Human neutrophils express high levels of CD53,an N-glycosylated pan-leukocyte antigen and the true homolog of the rat MRC-OX-44 antigen. CD53 is expressed on B cells,monocytes,macrophages,neutrophils,single (CD4 or CD8) positive thymocytes and peripheral T cells.
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