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Anti-CD3(AF488) Monoclonal Antibody - SAlexa Fluor 750
Cat: K010903M - SAlexa Fluor 750
Summary:
【Product name】:Anti-CD3(AF488) Monoclonal Antibody - SAlexa Fluor 750 【Source】:Mouse
【Isotype】:IgG1,κ
【Gene ID】:12501 【Swiss Prot】:P22646
【Tested applications】:FCM
【Recommended dilution】:FCM 5uL/Test.
【Storage】:Store at 4℃ in dark.Do not freeze.
Background:
The protein encoded by this gene is the CD3-epsilon polypeptide,which together with CD3-gamma,-delta and -zeta,and the T-cell receptor alpha/beta and gamma/delta heterodimers,forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon,gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq,Jul 2008].
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