Anti-CD41(AF488) Monoclonal Antibody - SAlexa Fluor 647
Cat: K010909M - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-CD41(AF488) Monoclonal Antibody - SAlexa Fluor 647 | 【Source】：Mouse |
| 【Isotype】：IgG1 | |
| 【Gene ID】：3674 | 【Swiss Prot】：P08514 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Storage】：Store at 4℃ in dark.Do not freeze. | |
Background:
Integrin alpha 2b (CD41) is a calcium-dependent，noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex，gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen，von Willebrand factor，fibronectin，vitronectin，and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
Verified picture: