Anti-CDKN1C Polyclonal Antibody - FITC
Cat: K114780P - FITC
Summary:
| 【Product name】：Anti-CDKN1C Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1028 | 【Swiss Prot】：P49918 |
| 【Observed】：37kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CDKN1C | |
| 【Public Immunogen Range】：266-316/316aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is imprinted; with preferential expression of the maternal allele. The encoded protein is a tight-binding; strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome; suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq; Oct 2010]
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