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Anti-PGRMC2 Polyclonal Antibody - FITC
Cat: K114793P - FITC
Summary:
【Product name】:Anti-PGRMC2 Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10424 【Swiss Prot】:O15173
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human PGRMC2
【Public Immunogen Range】:100-150/223aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity. May serve as a universal non-classical progesterone receptor in the uterus (Probable. Intracellular heme chaperone required for delivery of labile; or signaling heme; to the nucleus (By similarity. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat; which has a high demand for heme; delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity.
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